Recombinant human DERP6/ELP5 protein
Elongator acetyltransferase complex subunit 5, also known as ELP5, acts as subunit of the RNA polymerase II elongator complex, which is a histone acetyltransferase component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. Elongator may play a role in chromatin remodeling and is involved in acetylation of histones H3 and probably H4. This protein is involved in cell migration. Recombinant human ELP5 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.25 mg/mL (determined by Bradford assay)
Purity
> 80% by SDS-PAGE
Molecular Weight
37.2 kDa (339aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Yuan J., et al. (2006) Mol. Biol. Rep. 33:151-158; ; Zhang Q.-H., et al. (2000) Genome Res. 10:1546-1560
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 20% glycerol, 1mM DTT
Scientific Category
Epigenomics (Transcription & Translation)
NCBI Accession Number
NP_056177
Uniprot Accession Number
Q8TE02
Species
Human
AA Sequence
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