Recombinant human MIEN1 protein
MIEN1 belongs to the SelWTH family. This protein Increases cell migration by inducing filopodia formation at the leading edge of migrating cells and plays a role in regulation of apoptosis, possibly through control of CASP3. It also may be involved in a redox-related process. Recombinant human MIEN1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Migration and invasion enhancer 1, C17orf37, C35, ORB3, RDX12, XTP4
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by Bradford assay)
Purity
> 95% by SDS-PAGE
Molecular Weight
14.5 kDa (135aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Dasgupta, S., et al. (2011) J. Biol. Chem. 286 (29), 25935-25946; ; Katz, E., et al. (2011) Anal Cell Pathol (Amst) 34 (1-2), 35-48
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT
Scientific Category
Cancer
NCBI Accession Number
NP_115715
Uniprot Accession Number
Q9BRT3
Species
Human
AA Sequence
MGSSHHHHHH SSGLVPRGSH MGSMSGEPGQ TSVAPPPEEV EPGSGVRIVV EYCEPCGFEA TYLELASAVK EQYPGIEIES RLGGTGAFEI EINGQLVFSK LENGGFPYEK DLIEAIRRAS NGETLEKITN SRPPC
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