Recombinant human CMC1 protein
CMC1 is required for mitochondrial cytochrome c oxidase (COX) assembly and respiration. It binds copper and may be involved in copper trafficking and distribution to COX and SOD1. Recombinant human CMC1 protein, fused to His-tag at N-terminus, was expressed in E. coli.
Product Specifications
Product Name Alternative
COX assembly mitochondrial protein homolog, C3orf68
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE, Denatured
Concentration
0.5 mg/mL (determined by Bradford assay)
Purity
> 85% by SDS-PAGE
Molecular Weight
14.9 kDa (129aa)
Additionnal Information
References & Citations
Hendrickson, S.L., et al. (2010) PLoS ONE 5 (9), E12862; ; Horn, D., et al. (2008) Mol. Cell. Biol. 28 (13), 4354-4364
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M uREA, 10% glycerol
Scientific Category
Metabolism
NCBI Accession Number
NP_872329
Uniprot Accession Number
Q7Z7K0
Species
Human
AA Sequence
MGSSHHHHHH SSGLVPRGSH MGSMALDPAD QHLRHVEKDV LIPKIMREKA KERCSEQVQD FTKCCKNSGV LMVVKCRKEN SALKECLTAY YNDPAFYEEC KMEYLKEREE FRKTGIPTKK RLQKLPTSM
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