Recombinant human Cathepsin F protein

Cathepsin F, also known as CTSF, belongs to the cathepsin family. Cathepsins are papain family cysteine proteinases that represent a major component of the lysosomal proteolytic system. The CTSF gene is ubiquitously expressed, and it maps to chromosome 11q13, close to the gene encoding cathepsin W. CTSF is thought to play a role in normal protein catabolism, and because it is highly expressed in some cancer cell lines, it may be involved in degradative processes occurring during tumor progression. Recombinant human CTSF protein, fused to His-tag at N-terminus, was expressed in E. coli.

Product Specifications

Product Name Alternative

CTSF, Cathepsin F, CATSF, CLN13

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE, Denatured

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

26 kDa (237aa)

Additionnal Information

Cathepsin F, Cathepsin F, CATSF, CLN13, ATGP2259-10 µg, ATGP2259-20 µg, ATGP2259-50 µg, ATGP2259-100 µg, ATGP2259-250 µg, ATGP2259-500 µg, ATGP2259-1 mg, ATGP2259-10, ATGP2259-20, ATGP2259-50, ATGP2259-100, ATGP2259-250, ATGP2259-500, ATGP2259-1

References & Citations

Turk B., et al. (1997) Biol Chem. 378:141-150.; ; Wang B., et al. (1998) J Biol. 273:32000-32008.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol

Scientific Category

Immunology

NCBI Accession Number

NP_003784

Uniprot Accession Number

Q9UBX1

Species

Human

AA Sequence

APPEWDW RSKGAVTKVK DQGMCGSCWA FSVTGNVEGQ WFLNQGTLLS LSEQELLDCD KMDKACMGGL PSNAYSAIKN LGGLETEDDY SYQGHMQSCN FSAEKAKVYI NDSVELSQNE QKLAAWLAKR GPISVAINAF GMQFYRHGIS RPLRPLCSPW LIDHAVLLVG YGNRSDVPFW AIKNSWGTDW GEKGYYYLHR GSGACGVNTM ASSAVVD