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Recombinant human CEACAM21 protein

CEACAM21 is a member of the family of carcinoembryonic antigen-related cell adhesion molecules (CEACAMs), which are used by several bacterial pathogens to bind and invade host cells. The transmembrane protein directs phagocytosis of several bacterial species that is dependent on the small GTPase Rac. It is thought to serve an important role in controlling human-specific pathogens by the innate immune system. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. Recombinant human CEACAM21 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Product Specifications

Product Name Alternative

Carcinoembryonic antigen-related cell adhesion molecule 21, R29124_1, CEA cell adhesion molecule 21

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE, Denatured

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

25 kDa (229aa)

Additionnal Information

CEACAM21, Carcinoembryonic antigen-related cell adhesion molecule 21, CEACAM3, R29124_1, ATGP2254-10 µg, ATGP2254-20 µg, ATGP2254-50 µg, ATGP2254-100 µg, ATGP2254-250 µg, ATGP2254-500 µg, ATGP2254-1 mg, ATGP2254-10, ATGP2254-20, ATGP2254-50, ATGP2254-100, ATGP2254-250, ATGP2254-500, ATGP2254-1

References & Citations

Schmitter T, Agerer F, et al. (2004) . J Exp Med. 199 (1) :35-46.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol

Scientific Category

Immunology

NCBI Accession Number

NP_001091976

Uniprot Accession Number

Q3KPI0

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MGSWLFIASA PFEVAEGENV HLSVVYLPEN LYSYGWYKGK TVEPNQLIAA YVIDTHVRTP GPAYSGRETI SPSGDLHFQN VTLEDTGYYN LQVTYRNSQI EQASHHLRVY ESVAQPSIQA SSTTVTEKGS VVLTCHTNNT GTSFQWIFNN QRLQVTKRMK LSWFNHVLTI DPIRQEDAGE YQCEVSNPVS SNRSDPLKLT VKSDDNTLG

Frequently Asked Questions

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