Recombinant human ZMAT3 protein

ZMAT3 is a protein containing three zinc finger domains and a nuclear localization signal. The mRNA and the protein of this gene are upregulated by wildtype p53 and overexpression of this gene inhibits tumor cell growth, suggesting that this gene may have a role in the p53-dependent growth regulatory pathway. Alternative splicing of this gene results in two transcript variants encoding two isoforms differing in only one amino acid. Recombinant human ZMAT3 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Zinc finger matrin-type protein 3, PAG608, WIG-1, WIG1

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.25 mg/mL (determined by Bradford assay)

Purity

> 85% by SDS-PAGE

Molecular Weight

34.4 kDa (312aa) confirmed by MALDI-TOF

Additionnal Information

ZMAT3, Zinc finger matrin-type protein 3, PAG608, WIG-1, WIG1, ATGP2252-10 µg, ATGP2252-20 µg, ATGP2252-50 µg, ATGP2252-100 µg, ATGP2252-250 µg, ATGP2252-500 µg, ATGP2252-1 mg, ATGP2252-10, ATGP2252-20, ATGP2252-50, ATGP2252-100, ATGP2252-250, ATGP2252-500, ATGP2252-1

References & Citations

Hellborg F., et al. (2001) Oncogene. 20:5466-5474; ; Mendez Vidal C., et al. (2006) FEBS Lett. 580:4401-4408

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 50% glycerol, 2mM DTT

Scientific Category

Metabolism

NCBI Accession Number

NP_071915.1

Uniprot Accession Number

Q9HA38

Species

Human

AA Sequence

MILLQHA VLPPPKQPSP SPPMSVATRS TGTLQLPPQK PFGQEASLPL AGEEELSKGG EQDCALEELC KPLYCKLCNV TLNSAQQAQA HYQGKNHGKK LRNYYAANSC PPPARMSNVV EPAATPVVPV PPQMGSFKPG GRVILATEND YCKLCDASFS SPAVAQAHYQ GKNHAKRLRL AEAQSNSFSE SSELGQRRAR KEGNEFKMMP NRRNMYTVQN NSAGPYFNPR SRQRIPRDLA MCVTPSGQFY CSMCNVGAGE EMEFRQHLES KQHKSKVSEQ RYRNEMENLG YV