Recombinant human PSG5 protein
PSG5 is a member of the PSG family, a group of closely related secreted glycoproteins that are highly expressed in fetal placental syncytiotrophoblast cells. PSGs become detectable in serum during the first two to three weeks of pregnancy and increase as the pregnancy progresses, eventually representing the most abundant fetal protein in the maternal blood at term. PSG5 function to stimulate secretion of TH2-type cytokines from monocytes, and they may also modulate the maternal immune system during pregnancy, thereby protecting the semi-allotypic fetus from rejection. Recombinant human PSG5 protein, fused to His-tag at N-terminus, was expressed in E. coli.
Product Specifications
Product Name Alternative
Pregnancy-specific beta-1-glycoprotein 5, FL-NCA-3, PSG
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE, Denatured
Concentration
0.5 mg/mL (determined by Bradford assay)
Purity
> 80% by SDS-PAGE
Molecular Weight
36.4 kDa (324aa)
Additionnal Information
References & Citations
Chan W Y., et al. (1991) Mol Cell Biochem.106:161-170; ; Panzetta Dutari G M., et al. (2000) Biochem J. 2:511-519.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 1M urea, 10% glycerol
Scientific Category
Other
NCBI Accession Number
NP_001123486
Uniprot Accession Number
Q15238
Species
Human
AA Sequence
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