Recombinant human THAP3 protein

THAP3 is a component of a THAP1/THAP3-HCFC1-OGT complex that is required for the regulation of the transcriptional activity of RRM1. This protein is highly expressed in heart, skeletal muscle and placenta. Recombinant human THAP3 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

THAP domain-containing protein 3 isoform 3, THAP domain containing, apoptosis associated protein 3

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.25 mg/mL (determined by Bradford assay)

Purity

> 85% by SDS-PAGE

Molecular Weight

29.4 kDa (262aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)

Additionnal Information

THAP3, THAP domain-containing protein 3 isoform 3, THAP domain containing, apoptosis associated protein 3, ATGP2247-10 µg, ATGP2247-20 µg, ATGP2247-50 µg, ATGP2247-100 µg, ATGP2247-250 µg, ATGP2247-500 µg, ATGP2247-1 mg, ATGP2247-10, ATGP2247-20, ATGP2247-50, ATGP2247-100, ATGP2247-250, ATGP2247-500, ATGP2247-1

References & Citations

Bessiere D., et al. (2008) J Biol Chem. 283:4352-4363; ; Plasilova M., et al. (2004) Eur J Hum Genet. 12:365-371.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 50% glycerol, 2mM DTT

Scientific Category

Epigenomics (Transcription & Translation)

NCBI Accession Number

NP_001182682

Uniprot Accession Number

Q8WTV1

Species

Human

AA Sequence

MPKSCAA RQCCNRYSSR RKQLTFHRFP FSRPELLKEW VLNIGRGNFK PKQHTVICSE HFRPECFSAF GNRKNLKHNA VPTVFAFQDP TQQVRENTDP ASERGNASSS QKEKVLPEAG AGEDSPGRNM DTALEELQLP PNAEGHVKQV SPRRPQATEA VGRPTGPAGL RRTPNKQPSD HSYALLDLDS LKKKLFLTLK ENEKLRKRLQ AQRLVMRRMS SRLRACKGHQ GLQARLGPEQ QS