Recombinant human GIMAP6 protein

GIMAP6 is a member of the GTPases of immunity-associated proteins (GIMAP) family. GIMAP proteins contain GTP-binding and coiled-coil motifs, and may play roles in the regulation of cell survival. Decreased expression of this gene may play a role in non-small cell lung cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, which is found in a cluster with seven additional GIMAP genes on the long arm of chromosome 7. Recombinant human GIMAP6 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

GTPase IMAP family member 6 isoform 1, IAN-2, IAN-6, IAN2, IAN6

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by Bradford assay)

Purity

> 85% by SDS-PAGE

Molecular Weight

35 kDa (315aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)

Additionnal Information

GIMAP6, GTPase IMAP family member 6 isoform 1, IAN-2, IAN-6, IAN2, IAN6, ATGP2245-10 µg, ATGP2245-20 µg, ATGP2245-50 µg, ATGP2245-100 µg, ATGP2245-250 µg, ATGP2245-500 µg, ATGP2245-1 mg, ATGP2245-10, ATGP2245-20, ATGP2245-50, ATGP2245-100, ATGP2245-250, ATGP2245-500, ATGP2245-1

References & Citations

Krucken J, Schroetel RM, et al. (2004) . Gene. 341:291-304.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 30% glycerol, 1mM DTT

Scientific Category

Cancer

NCBI Accession Number

NP_078987

Uniprot Accession Number

Q6P9H5

Species

Human

AA Sequence

MEEEEYE QIPQENPPEE LSQDPVLELS GGLREKEQKT PRRLRLILMG KTGSGKSATG NSILGRDVFE SKLSTRPVTK TSQRRSREWA GKELEVIDTP NILSPQVSPE VADAICQAIV LSAPGPHAVL LVTQLGRFTD EDQQVVRRLQ EVFGVGVLGH TILVFTRKED LAGGSLEDYV RETNNQALAW LDVTLARRHC GFNNRAQGEE QEAQLRELME KVEAIMWENE GDYYSNKAYQ YTQQNFRLKE LQERQVSQGQ GSEDVPGEES WLEGLSQIQK ESEEAHRCLL GKADL