Recombinant human IL-38/IL-1F10 protein

IL1F10 is a member of the interleukin 1 cytokine family. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. This cytokine is thought to participate in a network of interleukin 1 family members to regulate adapted and innate immune responses. Two alternatively spliced transcript variants encoding the same protein have been reported. Recombinant human IL1F10 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Interleukin 1 family member 10, Family of interleukin 1-theta, FIL1 theta, Interleukin-1 HY2, IL-1HY2, Interleukin-1 theta, IL-1 theta, Interleukin-38, IL-38, FIL1T, Interleukin-1 receptor antagonist FKSG75

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

19.1 kDa (172aa) confirmed by MALDI-TOF

Additionnal Information

Putatitve interleukin-1 receptor antagonist FKSG75, FIL1-theta, FKSG75, IL1HY2, Macrophagitve interleukin-1 2, ATGP2240-10 µg, ATGP2240-20 µg, ATGP2240-50 µg, ATGP2240-100 µg, ATGP2240-250 µg, ATGP2240-500 µg, ATGP2240-1 mg, ATGP2240-010, ATGP2240-020, ATGP2240-050, ATGP2240-100, ATGP2240-250, ATGP2240-500, ATGP2240-01M

References & Citations

Taylor, S.L., et al. (2002) Genomics 79 (5), 726-733; ; Nicklin, M.J., et al. (2002) Genomics 79 (5), 718-725

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 20% glycerol, 1mM DTT

Scientific Category

Hormones & Cytokines

NCBI Accession Number

NP_115945.3

Uniprot Accession Number

Q8WWZ1

Species

Human

AA Sequence

MCSLPMARYY IIKYADQKAL YTRDGQLLVG DPVADNCCAE KICTLPNRGL DRTKVPIFLG IQGGSRCLAC VETEEGPSLQ LEDVNIEELY KGGEEATRFT FFQSSSGSAF RLEAAAWPGW FLCGPAEPQQ PVQLTKESEP SARTKFYFEQ SW