Recombinant human HHEX protein

HHEX is a member of the homeobox family of transcription factors, many of which are involved in developmental processes. Expression in specific hematopoietic lineages suggests that this protein may play a role in hematopoietic differentiation. HHEX has been shown to interact with Promyelocytic leukemia protein. Recombinant human HHEX protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Hematopoietically-expressed homeobox protein HHEX, HEX, HMPH, HOX11L-PEN, PRH, PRHX

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.25 mg/mL (determined by Bradford assay)

Purity

> 85% by SDS-PAGE

Molecular Weight

32.4 kDa (293aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)

Additionnal Information

HHEX, Hematopoietically-expressed homeobox protein HHEX, HEX, HMPH, HOX11L-PEN, PRH, PRHX, ATGP2239-10 µg, ATGP2239-20 µg, ATGP2239-50 µg, ATGP2239-100 µg, ATGP2239-250 µg, ATGP2239-500 µg, ATGP2239-1 mg, ATGP2239-10, ATGP2239-20, ATGP2239-50, ATGP2239-100, ATGP2239-250, ATGP2239-500, ATGP2239-1

References & Citations

Topcu Z, Mack DL, et al. (1999) . Oncogene. 18 (50) :7091-100.; ; Minami T, Murakami T, et al. (2004) . J Biol Chem. 279 (20) :20626-35.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 40% glycerol, 1mM DTT

Scientific Category

Development

NCBI Accession Number

NP_002720

Uniprot Accession Number

Q03014

Species

Human

AA Sequence

MQYPHPG PAAGAVGVPL YAPTPLLQPA HPTPFYIEDI LGRGPAAPTP APTLPSPNSS FTSLVSPYRT PVYEPTPIHP AFSHHSAAAL AAAYGPGGFG GPLYPFPRTV NDYTHALLRH DPLGKPLLWS PFLQRPLHKR KGGQVRFSND QTIELEKKFE TQKYLSPPER KRLAKMLQLS ERQVKTWFQN RRAKWRRLKQ ENPQSNKKEE LESLDSSCDQ RQDLPSEQNK GASLDSSQCS PSPASQEDLE SEISEDSDQE VDIEGDKSYF NAG