Recombinant human FAM84A/LRATD1 protein

FAM84A belongs to the FAM84 family of proteins and is predominantly expressed in testis. FAM84A localizes to a subcellular membrane region where there is no contact between neighboring cells and is believed to play a role in cell morphology and motility. More specifically, the expression of FAM84A increases cell motility. FAM84A is up-regulated in colorectal cancer lung cancer, pancreatic cancer, cholangiocarcinoma and bladder cancer tissues. Via its ability to increase cell motility, FAM84A may contribute to the invasion and metastasis of cancer cells. Recombinant human FAM84A protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

LRAT domain containing 1, Family with sequence similarity 84 member A, Neurological/sensory 1, Protein FAM84A, NSE1, PP11517

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

34.9 kDa (315aa) confirmed by MALDI-TOF

Additionnal Information

FAM84A, protein FAM84A, NSE1, PP11517, ATGP2224-10 µg, ATGP2224-20 µg, ATGP2224-50 µg, ATGP2224-100 µg, ATGP2224-250 µg, ATGP2224-500 µg, ATGP2224-1 mg, ATGP2224-10, ATGP2224-20, ATGP2224-50, ATGP2224-100, ATGP2224-250, ATGP2224-500, ATGP2224-1

References & Citations

Kobayashi, T., et al. (2006) Int. J. Oncol. 29 (2), 341-347

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT

Scientific Category

Other

NCBI Accession Number

NP_660158

Uniprot Accession Number

Q96KN4

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MGSMGNQLDR ITHLNYSELP TGDPSGIEKD ELRVGVAYFF SDDEEDLDER GQPDKFGVKA PPGCTPCPES PSRHHHHLLH QLVLNETQFS AFRGQECIFS KVSGGPQGAD LSVYAVTALP ALCEPGDLLE LLWLQPAPEP PAPAPHWAVY VGGGQIIHLH QGEIRQDSLY EAGAANVGRV VNSWYRYRPL VAELVVQNAC GHLGLKSEEI CWTNSESFAA WCRFGKREFK AGGEVPAGTQ PPQQQYYLKV HLGENKVHTA RFHSLEDLIR EKRRIDASGR LRVLQELADL VDDKE