Recombinant human Activin C protein

INHBC is the beta C chain of inhibin, a member of the TGF-beta superfamily. This subunit forms heterodimers with beta A and beta B subunits. Inhibins and activins, also members of the TGF-beta superfamily, are hormones with opposing actions and are involved in hypothalamic, pituitary, and gonadal hormone secretion, as well as growth and differentiation of various cell types. Recombinant human INHBC protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Inhibin beta C chain, IHBC

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by Bradford assay)

Purity

> 85% by SDS-PAGE

Molecular Weight

14.9 kDa (139aa) confirmed by MALDI-TOF

Additionnal Information

Activin C, Inhibin beta C chain, IHBC, ATGP2223-10 µg, ATGP2223-20 µg, ATGP2223-50 µg, ATGP2223-100 µg, ATGP2223-250 µg, ATGP2223-500 µg, ATGP2223-1 mg, ATGP2223-10, ATGP2223-20, ATGP2223-50, ATGP2223-100, ATGP2223-250, ATGP2223-500, ATGP2223-1

References & Citations

Hoetten G., et al. (1995) Biochem. Biophys. Res. Commun. 206:608-613; ; Thomas T.Z., et al. (1998) Prostate. 34:34-43

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT

Scientific Category

Hormones & Cytokines

NCBI Accession Number

NP_005529

Uniprot Accession Number

P55103

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MGSGIDCQGG SRMCCRQEFF VDFREIGWHD WIIQPEGYAM NFCIGQCPLH IAGMPGIAAS FHTAVLNLLK ANTAAGTTGG GSCCVPTARR PLSLLYYDRD SNIVKTDIPD MVVEACGCS