Recombinant human Activin C protein
INHBC is the beta C chain of inhibin, a member of the TGF-beta superfamily. This subunit forms heterodimers with beta A and beta B subunits. Inhibins and activins, also members of the TGF-beta superfamily, are hormones with opposing actions and are involved in hypothalamic, pituitary, and gonadal hormone secretion, as well as growth and differentiation of various cell types. Recombinant human INHBC protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Inhibin beta C chain, IHBC
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by Bradford assay)
Purity
> 85% by SDS-PAGE
Molecular Weight
14.9 kDa (139aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Hoetten G., et al. (1995) Biochem. Biophys. Res. Commun. 206:608-613; ; Thomas T.Z., et al. (1998) Prostate. 34:34-43
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT
Scientific Category
Hormones & Cytokines
NCBI Accession Number
NP_005529
Uniprot Accession Number
P55103
Species
Human
AA Sequence
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