Recombinant human MD-1 protein

LY86 is highly expressed in B-cells, monocytes and tonsil. This protein may cooperate with CD180 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) and cytokine production. It is important for efficient CD180 cell surface expression. Recombinant human LY86 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Product Specifications

Product Name Alternative

Lymphocyte antigen 86, lymphocyte antigen 86, dJ80N2.1, MD-1, MMD-1, RP1-80N2.1

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE, Denatured

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 85% by SDS-PAGE

Molecular Weight

18.1 kDa (165aa)

Additionnal Information

MD1, Lymphocyte antigen 86, lymphocyte antigen 86, dJ80N2.1, MD-1, MMD-1, RP1-80N2.1, ATGP2217-10 µg, ATGP2217-20 µg, ATGP2217-50 µg, ATGP2217-100 µg, ATGP2217-250 µg, ATGP2217-500 µg, ATGP2217-1 mg, ATGP2217-10, ATGP2217-20, ATGP2217-50, ATGP2217-100, ATGP2217-250, ATGP2217-500, ATGP2217-1

References & Citations

Miura Y., Shimazu R, et al. (1998) Blood 92:2815-2822

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing, 10% glycerol, 0.4M urea

Scientific Category

Immunology

NCBI Accession Number

NP_004262

Uniprot Accession Number

O95711

Species

Human

AA Sequence

GGGGKAW PTHVVCSDSG LEVLYQSCDP LQDFGFSVEK CSKQLKSNIN IRFGIILRED IKELFLDLAL MSQGSSVLNF SYPICEAALP KFSFCGRRKG EQIYYAGPVN NPEFTIPQGE YQVLLELYTE KRSTVACANA TIMCS