Recombinant human MD-1 protein
LY86 is highly expressed in B-cells, monocytes and tonsil. This protein may cooperate with CD180 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) and cytokine production. It is important for efficient CD180 cell surface expression. Recombinant human LY86 protein, fused to His-tag at N-terminus, was expressed in E. coli.
Product Specifications
Product Name Alternative
Lymphocyte antigen 86, lymphocyte antigen 86, dJ80N2.1, MD-1, MMD-1, RP1-80N2.1
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE, Denatured
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 85% by SDS-PAGE
Molecular Weight
18.1 kDa (165aa)
Additionnal Information
References & Citations
Miura Y., Shimazu R, et al. (1998) Blood 92:2815-2822
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing, 10% glycerol, 0.4M urea
Scientific Category
Immunology
NCBI Accession Number
NP_004262
Uniprot Accession Number
O95711
Species
Human
AA Sequence
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