Recombinant human IL-17F protein
IL17F is a cytokine that shares sequence similarity with IL17. This cytokine is expressed by activated T cells, and has been shown to stimulate the production of several other cytokines, including IL6, IL8, and CSF2/GM_CSF. This cytokine is also found to inhibit the angiogenesis of endothelial cells and induce endothelial cells to produce IL2, TGFB1/TGFB, and monocyte chemoattractant protein-1. Recombinant human IL17F protein, fused to His-tag at N-terminus, was expressed in E. coli.
Product Specifications
Product Name Alternative
CANDF6, IL-17F, Interleukin-17F, Interleukin-2, Macrophagleukin-17F, ML-1
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE, Denatured
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 85% by SDS-PAGE
Molecular Weight
17.6 kDa (158aa)
Additionnal Information
References & Citations
Starnes T., Robertson M.J. et al. (2001) . J. Immunol. 167:4137-4140.; ; Puel A., Cypowyj S., Bustamante J. et al. (2011) . Science 332:65-68
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing, 10% glycerol, 0.4M urea
Scientific Category
Hormones & Cytokines
NCBI Accession Number
NP_443104
Uniprot Accession Number
Q96PD4
Species
Human
AA Sequence
RKIPK VGHTFFQKPE SCPPVPGGSM KLDIGIINEN QRVSMSRNIE SRSTSPWNYT VTWDPNRYPS EVVQAQCRNL GCINAQGKED ISMNSVPIQQ ETLVVRRKHQ GCSVSFQLEK VLVTVGCTCV TPVIHHVQ
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