Recombinant human SCG3 protein

SCG3 is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. Granins may serve as precursors for biologically active peptides. Some granins have been shown to function as helper proteins in sorting and proteolytic processing of prohormones; however, the function of this protein is unknown. Recombinant human SCG3 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Secretogranin-3 isoform 1, SGIII

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by Bradford assay)

Purity

> 85% by SDS-PAGE

Molecular Weight

53 kDa (472aa)

Additionnal Information

SCG3, Secretogranin-3 isoform 1, SGIII, ATGP2213-10 µg, ATGP2213-20 µg, ATGP2213-50 µg, ATGP2213-100 µg, ATGP2213-250 µg, ATGP2213-500 µg, ATGP2213-1 mg, ATGP2213-10, ATGP2213-20, ATGP2213-50, ATGP2213-100, ATGP2213-250, ATGP2213-500, ATGP2213-1

References & Citations

Tanabe A, Yanagiya T, et al. (2007) . J Clin Endocrinol Metab. 92 (3) :1145-54. ; ; Hosaka M, Suda M, et al. (2004) . J Biol Chem. 279 (5) :3627-34.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 20% glycerol, 1mM DTT

Scientific Category

Neuroscience

NCBI Accession Number

NP_037375

Uniprot Accession Number

Q8WXD2

Species

Human

AA Sequence

FPKPGGS QDKSLHNREL SAERPLNEQI AEAEEDKIKK TYPPENKPGQ SNYSFVDNLN LLKAITEKEK IEKERQSIRS SPLDNKLNVE DVDSTKNRKL IDDYDSTKSG LDHKFQDDPD GLHQLDGTPL TAEDIVHKIA ARIYEENDRA VFDKIVSKLL NLGLITESQA HTLEDEVAEV LQKLISKEAN NYEEDPNKPT SWTENQAGKI PEKVTPMAAI QDGLAKGEND ETVSNTLTLT NGLERRTKTY SEDNFEELQY FPNFYALLKS IDSEKEAKEK ETLITIMKTL IDFVKMMVKY GTISPEEGVS YLENLDEMIA LQTKNKLEKN ATDNISKLFP APSEKSHEET DSTKEEAAKM EKEYGSLKDS TKDDNSNPGG KTDEPKGKTE AYLEAIRKNI EWLKKHDKKG NKEDYDLSKM RDFINKQADA YVEKGILDKE EAEAIKRIYS SL