Recombinant human CNP protein
NPPC is proteolytically processed to form a secreted hormone of the natriuretic peptide family. The hormone regulates the growth and differentiation of cartilaginous growth plate chondrocytes and may also be vasoactive and natriuretic. Recombinant human NPPC protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
C-type natriuretic peptide, C-type natriuretic peptide, CNP, CNP2
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.25 mg/mL (determined by BCA assay)
Purity
> 85% by SDS-PAGE
Molecular Weight
13.2 kDa (126aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Thompson, I.R., et al. (2012) Endocr. Relat. Cancer 19 (4), 497-508; ; Kuehnl, A., et al. (2012) Eur J Vasc Endovasc Surg 43 (6), 649-654;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol
Scientific Category
Hormones & Cytokines
NCBI Accession Number
NP_077720.1
Uniprot Accession Number
P23582
Species
Human
AA Sequence
KPGAPPK VPRTPPAEEL AEPQAAGGGQ KKGDKAPGGG GANLKGDRSR LLRDLRVDTK SRAAWARLLQ EHPNARKYKG ANKKGLSKGC FGLKLDRIGS MSGLGC
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