Recombinant human CXADR protein

CXADR is a type I membrane receptor for group B coxsackieviruses and subgroup C adenoviruses. Several transcript variants encoding different isoforms have been found for this gene. Pseudogenes of this gene are found on chromosomes 15, 18, and 21. Recombinant human CXADR protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Coxsackievirus and adenovirus receptor isoform 1, CAR; CAR4/6; HCAR

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

26 kDa (241aa) confirmed by MALDI-TOF

Additionnal Information

CXADR, Coxsackievirus and adenovirus receptor isoform 1, CAR; CAR4/6; HCAR, ATGP2201-10 µg, ATGP2201-20 µg, ATGP2201-50 µg, ATGP2201-100 µg, ATGP2201-250 µg, ATGP2201-500 µg, ATGP2201-1 mg, ATGP2201-10, ATGP2201-20, ATGP2201-50, ATGP2201-100, ATGP2201-250, ATGP2201-500, ATGP2201-1

References & Citations

Burckhardt CJ, Suomalainen M, et al. (2011) . Cell Host Microbe. 10 (2) :105-17.; ; Hussain F, Morton PE, et al. (2011) . PLoS One. 6 (8) :e23056. ;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT

Scientific Category

Signal Transduction

NCBI Accession Number

NP_001329

Uniprot Accession Number

P78310

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MGSLSITTPE EMIEKAKGET AYLPCKFTLS PEDQGPLDIE WLISPADNQK VDQVIILYSG DKIYDDYYPD LKGRVHFTSN DLKSGDASIN VTNLQLSDIG TYQCKVKKAP GVANKKIHLV VLVKPSGARC YVDGSEEIGS DFKIKCEPKE GSLPLQYEWQ KLSDSQKMPT SWLAEMTSSV ISVKNASSEY SGTYSCTVRN RVGSDQCLLR LNVVPPSNKA G