Recombinant human MEOX2 protein
Homeobox protein MOX-2, also known as MEOX2, belongs to a family of nonclustered, diverged homeobox genes that are expressed in overlapping patterns in the paraxial mesoderm and its derivatives. It may play a role in the regulation of vertebrate limb myogenesis. Mutations in the related mouse MEOX2 may be associated with craniofacial and/or skeletal abnormalities, in addition to neurovascular dysfunction observed in Alzheimer's disease. Recombinant human MEOX2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Homeobox protein MOX-2, Homeobox protein MOX-2, GAX, MOX2
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.25 mg/mL (determined by Bradford assay)
Purity
> 95% by SDS-PAGE
Molecular Weight
15.9 kDa (140aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Candia A F., et al. (1996) Int J Dev Biol. 40:1179-1184; ; Mankoo B S., et al. (1999) Nature. 400:69-73.;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 40% glycerol, 2mM DTT
Scientific Category
Neuroscience
NCBI Accession Number
NP_005915
Uniprot Accession Number
P50222
Species
Human
AA Sequence
RKERTAF TKEQIRELEA EFAHHNYLTR LRRYEIAVNL DLTERQVKVW FQNRRMKWKR VKGGQQGAAA REKELVNVKK GTLLPSELSG IGAATLQQTG DSIANEDSHD SDHSSEHAHL
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