Recombinant human IPP-3/PPP1R11 protein
Protein phosphatase 1 regulatory subunit 11, also known as PPP1R11, is a 126 amino acid protein that is expressed in a variety of both adult and fetal tissues. PPP1R11 functions as an inhibitor of PP1 (protein phosphatase 1), specifically exhibiting a sensitivity toward the metal-independent and metal-dependent forms of PP1. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer, suggesting the presence of a cancer susceptibility locus. Recombinant human PPP1R11 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.25 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
16.3 kDa (149aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)
Additionnal Information
References & Citations
Giffon T., et al. (1996) Immunogenrtics. 44:331-339; ; Zhang J., et al. (1998) Biochemistry. 37:16728-16734.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 20% glycerol, 1mM DTT
Scientific Category
Signal Transduction
NCBI Accession Number
NP_068778
Uniprot Accession Number
O60927
Species
Human
AA Sequence
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
Recombinant Arabidopsis thaliana Proline-rich receptor-like protein kinase PERK9 (PERK9), partial
Recombinant Arabidopsis thaliana Proline-rich receptor-like protein kinase PERK9 (PERK9), partial
Recombinant Arabidopsis thaliana Proline-rich receptor-like protein kinase PERK9 (PERK9), partial
Recombinant Arabidopsis thaliana Proline-rich receptor-like protein kinase PERK9 (PERK9), partial