Recombinant human CDK3 protein
CDK3 is a member of the cyclin-dependent protein kinase family. The protein promotes entry into S phase, in part by activating members of the E2F family of transcription factors. The protein also associates with cyclin C and phosphorylates the retinoblastoma 1 protein to promote exit from G0. Recombinant human CDK3 protein, fused to His-tag at N-terminus, was expressed in E. coli.
Product Specifications
Product Name Alternative
Cyclin-dependent kinase 3, CDKN3, Cell division protein kinase 3, Cyclin dependent kinase 3
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE, Denatured
Concentration
0.25 mg/mL (determined by Bradford assay)
Purity
> 85% by SDS-PAGE
Molecular Weight
37.4 kDa (328aa)
Additionnal Information
References & Citations
MacLachlan T K., et al. (1995) Eukaryot Gene Expr. 5:127-156.; ; Braun K., et al. (1998) Oncogene. 17:2259-2269.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 1M urea, 10% glycerol
Scientific Category
Cell Cycle
NCBI Accession Number
NP_001249
Uniprot Accession Number
Q00526
Species
Human
AA Sequence
Frequently Asked Questions
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