Recombinant human CDK3 protein

CDK3 is a member of the cyclin-dependent protein kinase family. The protein promotes entry into S phase, in part by activating members of the E2F family of transcription factors. The protein also associates with cyclin C and phosphorylates the retinoblastoma 1 protein to promote exit from G0. Recombinant human CDK3 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Product Specifications

Product Name Alternative

Cyclin-dependent kinase 3, CDKN3, Cell division protein kinase 3, Cyclin dependent kinase 3

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE, Denatured

Concentration

0.25 mg/mL (determined by Bradford assay)

Purity

> 85% by SDS-PAGE

Molecular Weight

37.4 kDa (328aa)

Additionnal Information

CDK3, Cyclin-dependent kinase 3, CDKN3, Cell division protein kinase 3, Cyclin dependent kinase 3, ATGP2169-10 µg, ATGP2169-20 µg, ATGP2169-50 µg, ATGP2169-100 µg, ATGP2169-250 µg, ATGP2169-500 µg, ATGP2169-1 mg, ATGP2169-10, ATGP2169-20, ATGP2169-50, ATGP2169-100, ATGP2169-250, ATGP2169-500, ATGP2169-1

References & Citations

MacLachlan T K., et al. (1995) Eukaryot Gene Expr. 5:127-156.; ; Braun K., et al. (1998) Oncogene. 17:2259-2269.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 1M urea, 10% glycerol

Scientific Category

Cell Cycle

NCBI Accession Number

NP_001249

Uniprot Accession Number

Q00526

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MGSMDMFQKV EKIGEGTYGV VYKAKNRETG QLVALKKIRL DLEMEGVPST AIREISLLKE LKHPNIVRLL DVVHNERKLY LVFEFLSQDL KKYMDSTPGS ELPLHLIKSY LFQLLQGVSF CHSHRVIHRD LKPQNLLINE LGAIKLADFG LARAFGVPLR TYTHEVVTLW YRAPEILLGS KFYTTAVDIW SIGCIFAEMV TRKALFPGDS EIDQLFRIFR MLGTPSEDTW PGVTQLPDYK GSFPKWTRKG LEEIVPNLEP EGRDLLMQLL QYDPSQRITA KTALAHPYFS SPEPSPAARQ YVLQRFRH