What is the catalog number for Recombinant human PSTPIP1 protein?

The catalog number for Recombinant human PSTPIP1 protein is ATGP2158-100.

What sizes are available for Recombinant human PSTPIP1 protein?

Recombinant human PSTPIP1 protein is available in the following size(s): 100 µg.

Is Recombinant human PSTPIP1 protein in stock?

Recombinant human PSTPIP1 protein is currently made to order / not held in immediate stock. Contact us for lead time.

Recombinant human PSTPIP1 protein

PSTPIP1 binds to the cytoplasmic tail of CD2, an effector of T cell activation and adhesion, negatively affecting CD2-triggered T cell activation. The protein appears to be a scaffold protein and a regulator of the actin cytoskeleton. It has also been shown to bind ABL1, PTPN18, WAS, CD2AP, and PTPN12. Mutations in this gene are a cause of PAPA syndrome. Recombinant human PSTPIP1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Proline-serine-threonine phosphatase interacting protein 1, CD2BP1, CD2BP1L, CD2BP1S, H-PIP, PAPAS, PSTPIP

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

50kDa (439aa)

Additionnal Information

PSTPIP1, Proline-serine-threonine phosphatase interacting protein 1, CD2BP1, CD2BP1L, CD2BP1S, H-PIP, PAPAS, PSTPIP, ATGP2158-10 µg, ATGP2158-20 µg, ATGP2158-50 µg, ATGP2158-100 µg, ATGP2158-250 µg, ATGP2158-500 µg, ATGP2158-1 mg, ATGP2158-10, ATGP2158-20, ATGP2158-50, ATGP2158-100, ATGP2158-250, ATGP2158-500, ATGP2158-1

References & Citations

Shoham N.G., et al. (2003) Proc. Natl. Acad. Sci. u.S.A. 100:13501-13506; ; Wise C.A., et al. (2002) Hum. Mol. Genet. 11:961-969

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 20% glycerol, 1mM DTT

Scientific Category

Signal Transduction

NCBI Accession Number

NP_003969

Uniprot Accession Number

O43586

Species

Human

AA Sequence

MMPQLQF KDAFWCRDFT AHTGYEVLLQ RLLDGRKMCK DMEELLRQRA QAEERYGKEL VQIARKAGGQ TEINSLRASF DSLKQQMENV GSSHIQLALT LREELRSLEE FRERQKEQRK KYEAVMDRVQ KSKLSLYKKA MESKKTYEQK CRDADDAEQA FERISANGHQ KQVEKSQNKA RQCKDSATEA ERVYRQSIAQ LEKVRAEWEQ EHRTTCEAFQ LQEFDRLTIL RNALWVHSNQ LSMQCVKDDE LYEEVRLTLE GCSIDADIDS FIQAKSTGTE PPAPVPYQNY YDREVTPLTS SPGIQPSCGM IKRFSGLLHG SPKTTSLAAS AASTETLTPT PERNEGVYTA IAVQEIQGNP ASPAQEYRAL YDYTAQNPDE LDLSAGDILE VILEGEDGWW TVERNGQRGF VPGSYLEKL