Recombinant human RARRES1 protein

Retinoic acid receptor responder protein 1 isoform 1, also known as RARRES1, belongs to the TIGs (Tazarotene-induced gene) family. TIGs act as tumor suppressor genes in human cancers and are highly expressed in skin, hair follicles and endothelial cells as well as in pancreas, spleen and intestine. TIGs are activated by tazarotene and have been implicated as growth regulators that mediate the growth suppressive effects of retinoids. Recombinant human RARRES1 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Product Specifications

Product Name Alternative

Retinoic acid receptor responder protein 1 isoform 1, TIG1

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE, Denatured

Concentration

0.5 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

31.3 kDa (275aa)

Additionnal Information

RARRES1, Retinoic acid receptor responder protein 1 isoform 1, TIG1, ATGP2157-10 µg, ATGP2157-20 µg, ATGP2157-50 µg, ATGP2157-100 µg, ATGP2157-250 µg, ATGP2157-500 µg, ATGP2157-1 mg, ATGP2157-10, ATGP2157-20, ATGP2157-50, ATGP2157-100, ATGP2157-250, ATGP2157-500, ATGP2157-1

References & Citations

Kwong J., et al. (2005) J Cancer. 113:386-392.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol

Scientific Category

Cancer

NCBI Accession Number

NP_996846

Uniprot Accession Number

P49788

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MGSPDDPGQP QDAGVPRRLL QQAARAALHF FNFRSGSPSA LRVLAEVQEG RAWINPKEGC KVHVVFSTER YNPESLLQEG EGRLGKCSAR VFFKNQKPRP TINVTCTRLI EKKKRQQEDY LLYKQMKQLK NPLEIVSIPD NHGHIDPSLR LIWDLAFLGS SYVMWEMTTQ VSHYYLAQLT SVRQWKTNDD TIDFDYTVLL HELSTQEIIP CRIHLVWYPG KPLKVKYHCQ ELQTPEEASG TEEGSAVVPT ELSNF