Recombinant human RARRES1 protein
Retinoic acid receptor responder protein 1 isoform 1, also known as RARRES1, belongs to the TIGs (Tazarotene-induced gene) family. TIGs act as tumor suppressor genes in human cancers and are highly expressed in skin, hair follicles and endothelial cells as well as in pancreas, spleen and intestine. TIGs are activated by tazarotene and have been implicated as growth regulators that mediate the growth suppressive effects of retinoids. Recombinant human RARRES1 protein, fused to His-tag at N-terminus, was expressed in E. coli.
Product Specifications
Product Name Alternative
Retinoic acid receptor responder protein 1 isoform 1, TIG1
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE, Denatured
Concentration
0.5 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
31.3 kDa (275aa)
Additionnal Information
References & Citations
Kwong J., et al. (2005) J Cancer. 113:386-392.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol
Scientific Category
Cancer
NCBI Accession Number
NP_996846
Uniprot Accession Number
P49788
Species
Human
AA Sequence
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