Recombinant human UBXN2B protein

UBX domain-containing protein 2B, also known as uBXN2B, is a 331 amino acid protein that contains one uBX domain and one SEP domain. uBXN2B is required for ER and Golgi biogenesis and also plays a role in their maintenance during interphase, as well as their reassembly at the end of mitosis. Through interaction with VCP, uBXN2B forms a complex that has membrane fusion activity. Recombinant human uBXN2B protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

UBX domain-containing protein 2B, p37

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

39.5 kDa (354aa) confirmed by MALDI-TOF

Additionnal Information

UBXN2B, uBX domain-containing protein 2B, p37, ATGP2155-10 µg, ATGP2155-20 µg, ATGP2155-50 µg, ATGP2155-100 µg, ATGP2155-250 µg, ATGP2155-500 µg, ATGP2155-1 mg, ATGP2155-10, ATGP2155-20, ATGP2155-50, ATGP2155-100, ATGP2155-250, ATGP2155-500, ATGP2155-1

References & Citations

Uchiyama K., et al. (2006) Dev Cell. 11:803-816.; ; Tang D., et al. (2008) J Biol Chem. 283:6085-6094.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol

Scientific Category

Signal Transduction

NCBI Accession Number

NP_001071087

Uniprot Accession Number

Q14CS0

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MGSMAEGGGP EPGEQERRSS GPRPPSARDL QLALAELYED EVKCKSSKSN RPKATVFKSP RTPPQRFYSS EHEYSGLNIV RPSTGKIVNE LFKEAREHGA VPLNEATRAS GDDKSKSFTG GGYRLGSSFC KRSEYIYGEN QLQDVQILLK LWSNGFSLDD GELRPYNEPT NAQFLESVKR GEIPLELQRL VHGGQVNLDM EDHQDQEYIK PRLRFKAFSG EGQKLGSLTP EIVSTPSSPE EEDKSILNAV VLIDDSVPTT KIQIRLADGS RLIQRFNSTH RILDVRNFIV QSRPEFAALD FILVTSFPNK ELTDESLTLL EADILNTVLL QQLK