Recombinant human REXO2 protein

REXO2 is a 3'-to-5' exonuclease specific for small (primarily 5 nucleotides or less in length) single-stranded RNA and DNA oligomers. This protein may have a role in DNA repair, replication, and recombination, and in RNA processing and degradation. It may also be involved in resistance of human cells to uV-C-induced cell death through its role in the DNA repair process. Recombinant human REXO2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Oligoribonuclease mitochondrial, Oligoribonuclease, mitochondrial, REX2, RNA exonuclease 2 homolog (S. cerevisiae), CGI-114, REX2, RFN, SFN

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

26.8 kDa (235aa) confirmed by MALDI-TOF

Additionnal Information

REXO2, Oligoribonuclease mitochondrial, Oligoribonuclease, mitochondrial, REX2, RNA exonuclease 2 homolog (S. cerevisiae), CGI-114, REX2, RFN, SFN, ATGP2152-10 µg, ATGP2152-20 µg, ATGP2152-50 µg, ATGP2152-100 µg, ATGP2152-250 µg, ATGP2152-500 µg, ATGP2152-1 mg, ATGP2152-10, ATGP2152-20, ATGP2152-50, ATGP2152-100, ATGP2152-250, ATGP2152-500, ATGP2152-1

References & Citations

Lai CH, Chou CY, Ch'ang LY, Liu CS, Lin W . May 2000. Genome Res. 10 (5) : 703-13; ; Nguyen LH, Erzberger JP, Root J, Wilson DM .August 2000. J. Biol. Chem. 275 (34) : 25900-6.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 20% glycerol

Scientific Category

Epigenomics (Transcription & Translation)

NCBI Accession Number

NP_056338

Uniprot Accession Number

Q9Y3B8

Species

Human

AA Sequence

VREGGAA MAAGESMAQR MVWVDLEMTG LDIEKDQIIE MACLITDSDL NILAEGPNLI IKQPDELLDS MSDWCKEHHG KSGLTKAVKE STITLQQAEY EFLSFVRQQT PPGLCPLAGN SVHEDKKFLD KYMPQFMKHL HYRIIDVSTV KELCRRWYPE EYEFAPKKAA SHRALDDISE SIKELQFYRN NIFKKKIDEK KRKIIENGEN EKTVS