Recombinant human IL-13R alpha 2/IL13RA2 protein
IL13RA2 is closely related to Il13RA1, a subuint of the interleukin 13 receptor complex. This protein binds IL13 with high affinity, but lacks cytoplasmic domain, and does not appear to function as a signal mediator. It is reported to play a role in the internalization of IL13. Recombinant human IL13RA2 protein, fused to His-tag at N-terminus, was expressed in E. coli.
Product Specifications
Product Name Alternative
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE, Denatured
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 85% by SDS-PAGE
Molecular Weight
39.5 kDa (340aa)
Additionnal Information
References & Citations
Fujisawa, T., et al. (2012) Int. J. Cancer 131 (2), 344-356; ; Barderas, R., et al. (2012) Cancer Res. 72 (11), 2780-2790
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M uREA, 10% glycerol
Scientific Category
Immunology
NCBI Accession Number
NP_000631
Uniprot Accession Number
Q14627
Species
Human
AA Sequence
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