Recombinant human IL-13R alpha 2/IL13RA2 protein

IL13RA2 is closely related to Il13RA1, a subuint of the interleukin 13 receptor complex. This protein binds IL13 with high affinity, but lacks cytoplasmic domain, and does not appear to function as a signal mediator. It is reported to play a role in the internalization of IL13. Recombinant human IL13RA2 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Product Specifications

Product Name Alternative

Interleukin 13 receptor subunit alpha 2, IL-13 receptor subunit alpha-2, IL-13R subunit alpha-2, IL-13R-alpha-2, Interleukin-13-binding protein, CD213a2, IL13R, IL13BP, cancer/testis antigen 19, CT19

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE, Denatured

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 85% by SDS-PAGE

Molecular Weight

39.5 kDa (340aa)

Additionnal Information

IL13 R a2, interleukin-13 receptor subunit alpha-2 precursor, CD213A2, CT19, IL-13R, IL13BP, ATGP2139-10 µg, ATGP2139-20 µg, ATGP2139-50 µg, ATGP2139-100 µg, ATGP2139-250 µg, ATGP2139-500 µg, ATGP2139-1 mg, ATGP2139-10, ATGP2139-20, ATGP2139-50, ATGP2139-100, ATGP2139-250, ATGP2139-500, ATGP2139-1

References & Citations

Fujisawa, T., et al. (2012) Int. J. Cancer 131 (2), 344-356; ; Barderas, R., et al. (2012) Cancer Res. 72 (11), 2780-2790

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M uREA, 10% glycerol

Scientific Category

Immunology

NCBI Accession Number

NP_000631

Uniprot Accession Number

Q14627

Species

Human

AA Sequence

DTEIKVN PPQDFEIVDP GYLGYLYLQW QPPLSLDHFK ECTVEYELKY RNIGSETWKT IITKNLHYKD GFDLNKGIEA KIHTLLPWQC TNGSEVQSSW AETTYWISPQ GIPETKVQDM DCVYYNWQYL LCSWKPGIGV LLDTNYNLFY WYEGLDHALQ CVDYIKADGQ NIGCRFPYLE ASDYKDFYIC VNGSSENKPI RSSYFTFQLQ NIVKPLPPVY LTFTRESSCE IKLKWSIPLG PIPARCFDYE IEIREDDTTL VTATVENETY TLKTTNETRQ LCFVVRSKVN IYCSDDGIWS EWSDKQCWEG EDLSKKTLLR