Recombinant human MAGOHB protein
MAGOHB is involved in mRNA splicing and in the nonsense-mediated decay (NMD) pathway. Also, it is interacts with RBM8A and is part of the exon junction complex (EJC) containing NCBP1, NCBP2, RNPS1, RBM8A, SRRM1, NXF1, uPF3B, uPF2 and ALYREF/THOC4. Recombinant human MAGOHB protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Protein mago nashi homolog 2, mago-nashi homolog B (Drosophila), mago, magoh, MGN2
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.25 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
19.7 kDa (171aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Sjoblom T, Jones S, Wood LD, Parsons DW, Lin J, ., et al. 2006 Oct 13; ;314 (5797) :268-74.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 1mM DTT 30% glycerol, 0.15M NaCl
Scientific Category
Epigenomics (Transcription & Translation)
NCBI Accession Number
NP_060518
Uniprot Accession Number
Q96A72
Species
Human
AA Sequence
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