Recombinant human MAGOHB protein

MAGOHB is involved in mRNA splicing and in the nonsense-mediated decay (NMD) pathway. Also, it is interacts with RBM8A and is part of the exon junction complex (EJC) containing NCBP1, NCBP2, RNPS1, RBM8A, SRRM1, NXF1, uPF3B, uPF2 and ALYREF/THOC4. Recombinant human MAGOHB protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Protein mago nashi homolog 2, mago-nashi homolog B (Drosophila), mago, magoh, MGN2

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.25 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

19.7 kDa (171aa) confirmed by MALDI-TOF

Additionnal Information

MAGOHB, Protein mago nashi homolog 2, mago-nashi homolog B (Drosophila), mago, magoh, MGN2, ATGP2131-10 µg, ATGP2131-20 µg, ATGP2131-50 µg, ATGP2131-100 µg, ATGP2131-250 µg, ATGP2131-500 µg, ATGP2131-1 mg, ATGP2131-10, ATGP2131-20, ATGP2131-50, ATGP2131-100, ATGP2131-250, ATGP2131-500, ATGP2131-1

References & Citations

Sjoblom T, Jones S, Wood LD, Parsons DW, Lin J, ., et al. 2006 Oct 13; ;314 (5797) :268-74.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 1mM DTT 30% glycerol, 0.15M NaCl

Scientific Category

Epigenomics (Transcription & Translation)

NCBI Accession Number

NP_060518

Uniprot Accession Number

Q96A72

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MGSMAVASDF YLRYYVGHKG KFGHEFLEFE FRPDGKLRYA NNSNYKNDVM IRKEAYVHKS VMEELKRIID DSEITKEDDA LWPPPDRVGR QELEIVIGDE HISFTTSKIG SLIDVNQSKD PEGLRVFYYL VQDLKCLVFS LIGLHFKIKP I