Recombinant human FGF-14 protein
FGF14 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. A mutation in this gene is associated with autosomal dominant cerebral ataxia. Alternatively spliced transcript variants have been found for this gene. Recombinant human FGF14 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Fibroblast growth factor 14 isoform 1A, FGF-14, FHF-4, FHF4, SCA27
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.25 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
30kDa (271aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Smallwood PM, et al. (1996) . Proc Natl Acad Sci u S A. 93 (18) :9850-7.; ; Wozniak DF, Xiao M, Xu L, et al. (2007) . Neurobiol Dis. 26 (1) :14-26.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 50% glycerol, 5mM DTT
Scientific Category
Hormones & Cytokines
NCBI Accession Number
NP_004106
Uniprot Accession Number
Q92915
Species
Human
AA Sequence
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