Recombinant human FGF-14 protein

FGF14 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. A mutation in this gene is associated with autosomal dominant cerebral ataxia. Alternatively spliced transcript variants have been found for this gene. Recombinant human FGF14 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Fibroblast growth factor 14 isoform 1A, FGF-14, FHF-4, FHF4, SCA27

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.25 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

30kDa (271aa) confirmed by MALDI-TOF

Additionnal Information

FGF 14, FGF14, Fibroblast growth factor 14 isoform 1A, FGF-14, FHF-4, FHF 4, FHF4, SCA27, ATGP2128-10 µg, ATGP2128-20 µg, ATGP2128-50 µg, ATGP2128-100 µg, ATGP2128-250 µg, ATGP2128-500 µg, ATGP2128-1 mg, ATGP2128-010, ATGP2128-020, ATGP2128-050, ATGP2128-100, ATGP2128-250, ATGP2128-500, ATGP2128-01M

References & Citations

Smallwood PM, et al. (1996) . Proc Natl Acad Sci u S A. 93 (18) :9850-7.; ; Wozniak DF, Xiao M, Xu L, et al. (2007) . Neurobiol Dis. 26 (1) :14-26.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 50% glycerol, 5mM DTT

Scientific Category

Hormones & Cytokines

NCBI Accession Number

NP_004106

Uniprot Accession Number

Q92915

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MGSHMAAAIA SGLIRQKRQA REQHWDRPSA SRRRSSPSKN RGLCNGNLVD IFSKVRIFGL KKRRLRRQDP QLKGIVTRLY CRQGYYLQMH PDGALDGTKD DSTNSTLFNL IPVGLRVVAI QGVKTGLYIA MNGEGYLYPS ELFTPECKFK ESVFENYYVI YSSMLYRQQE SGRAWFLGLN KEGQAMKGNR VKKTKPAAHF LPKPLEVAMY REPSLHDVGE TVPKPGVTPS KSTSASAIMN GGKPVNKSKT T