Recombinant human THRSP protein

THRSP is similar to the gene product of S14, a rat gene whose expression is limited to liver and adipose tissue and is controlled by nutritional and hormonal factors. This gene has been shown to be expressed in liver and adipocytes, particularly in lipomatous modules. It is also found to be expressed in lipogenic breast cancers, which suggests a role in controlling tumor lipid metabolism. Recombinant human THRSP protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Thyroid hormone-inducible hepatic protein, Lpgp, LPGP1, S14, SPOT14, THRP

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

18.9 kDa (169aa) confirmed by MALDI-TOF

Additionnal Information

THRSP, Thyroid hormone-inducible hepatic protein, Lpgp, LPGP1, S14, SPOT14, THRP, ATGP2127-10 µg, ATGP2127-20 µg, ATGP2127-50 µg, ATGP2127-100 µg, ATGP2127-250 µg, ATGP2127-500 µg, ATGP2127-1 mg, ATGP2127-10, ATGP2127-20, ATGP2127-50, ATGP2127-100, ATGP2127-250, ATGP2127-500, ATGP2127-1

References & Citations

Taviaux S, Planells R, et al. (1997) . Cytogenet Cell Genet. 76 (3-4) :219-20.; ; Moncur JT, Park JP, et al. (2003) . Proc Natl Acad Sci u S A. 95 (12) :6989-94.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol

Scientific Category

Metabolism

NCBI Accession Number

NP_003242

Uniprot Accession Number

Q92748

Species

Human

AA Sequence

MQVLTKR YPKNCLLTVM DRYAAEVHNM EQVVMIPSLL RDVQLSGPGG QAQAEAPDLY TYFTMLKAIC VDVDHGLLPR EEWQAKVAGS EENGTAETEE VEDESASGEL DLEAQFHLHF SSLHHILMHL TEKAQEVTRK YQEMTGQVW