Recombinant human CEACAM7/CEA protein

CEACAM7 belongs to the immunoglobulin superfamily This protein contains 1 Ig-like C2-type (immunoglobulin-like) domain and 1 Ig-like V-type (immunoglobulin-like) domain. CEACAM7 is strongly down-regulated in colonic adenocarcinomas. Recombinant human CEACAM7 fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Carcinoembryonic antigen-related cell adhesion molecule 7, CEA, Carcinoembryonic antigen related cell adhesion molecule 7, CEA cell adhesion molecule 7, CGM2

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.25 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

25.7 kDa (230aa)

Additionnal Information

CGM2, CEACAM7, CEA cell adhesion molecule 7, CEA, Carcinoembryonic antigen-related cell adhesion molecule 7, Carcinoembryonic antigen related cell adhesion molecule 7, ATGP2125-10 µg, ATGP2125-20 µg, ATGP2125-50 µg, ATGP2125-100 µg, ATGP2125-250 µg, ATGP2125-500 µg, ATGP2125-1 mg, ATGP2125-010, ATGP2125-020, ATGP2125-050, ATGP2125-100, ATGP2125-250, ATGP2125-500, ATGP2125-01M

References & Citations

Thompson J, Seitz M, et al. (1997) . Cancer Res. 57 (9) :1776-84.; ; Kinugasa T, Kuroki M, et al. (1998) . Int J Cancer. 76 (1) :148-53.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol

Scientific Category

Cancer

NCBI Accession Number

AAI21133

Uniprot Accession Number

Q14002

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MGSTNIDVVP FNVAEGKEVL LVVHNESQNL YGYNWYKGER VHANYRIIGY VKNISQENAP GPAHNGRETI YPNGTLLIQN VTHNDAGIYT LHVIKENLVN EEVTRQFYVF SEPPKPSITS NNFNPVENKD IVVLTCQPET QNTTYLWWVN NQSLLVSPRL LLSTDNRTLV LLSATKNDIG PYECEIQNPV GASRSDPVTL NVRYESVQAS