Recombinant human COMMD7 protein
COMMD7 is a 200 amino acid protein that contains 1 COMM domain. This protein interacts (via COMM domain) with COMMD1 via its COMM domain. It also associates with the NF-kappa-B complex and suppresses its transcriptional activity. COMMD7 is widely expressed with highest expression in lung. Recombinant human COMMD7 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
COMM domain-containing protein 7, C20orf92, dJ1085F17.3
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
24.9 kDa (223aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Burstein, E., et al. (2005) J. Biol. Chem. 280 (23), 22222-22232
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT
Scientific Category
Signal Transduction
NCBI Accession Number
NP_444269
Uniprot Accession Number
Q86VX2
Species
Human
AA Sequence
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