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Recombinant human COMMD7 protein

COMMD7 is a 200 amino acid protein that contains 1 COMM domain. This protein interacts (via COMM domain) with COMMD1 via its COMM domain. It also associates with the NF-kappa-B complex and suppresses its transcriptional activity. COMMD7 is widely expressed with highest expression in lung. Recombinant human COMMD7 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

COMM domain-containing protein 7, C20orf92, dJ1085F17.3

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

24.9 kDa (223aa) confirmed by MALDI-TOF

Additionnal Information

COMMD7, COMM domain-containing protein 7, C20orf92, dJ1085F17.3, ATGP2123-10 µg, ATGP2123-20 µg, ATGP2123-50 µg, ATGP2123-100 µg, ATGP2123-250 µg, ATGP2123-500 µg, ATGP2123-1 mg, ATGP2123-10, ATGP2123-20, ATGP2123-50, ATGP2123-100, ATGP2123-250, ATGP2123-500, ATGP2123-1

References & Citations

Burstein, E., et al. (2005) J. Biol. Chem. 280 (23), 22222-22232

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT

Scientific Category

Signal Transduction

NCBI Accession Number

NP_444269

Uniprot Accession Number

Q86VX2

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MGSMGRLHCT EDPVPEAVGG DMQQLNQLGA QQFSALTEVL FHFLTEPKEV ERFLAQLSEF ATTNQISLGS LRSIVKSLLL VPNGALKKSL TAKQVQADFI TLGLSEEKAT YFSEKWKQNA PTLARWAIGQ TLMINQLIDM EWKFGVTSGS SELEKVGSIF LQLKLVVKKG NQTENVYIEL TLPQFYSFLH EMERVRTSME CFC

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