Recombinant human Sulfotransferase 1C4/SULT1C4 protein

Sulfotransferase 1C4, also known as SuLT1C4, belongs to the SuLT subfamily, responsible for transferring a sulfo moiety from PAPS to phenol-containing compounds. Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. SuLT1C4 catalyzes the sulfonation of p-nitrophenol and N-hydroxy-2-acetylaminofluorene, but not dopamine. Recombinant human SuLT1C4 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Sulfotransferase family 1C member 4, Sulfotransferase 1C4, ST1C4, Sulfotransferase 1C2, SULT1C2, Sulfotransferase family cytosolic 1C member 2, Sulfotransferase family cytosolic 1C member 4, SULT1C

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 95% by SDS-PAGE

Molecular Weight

37.6 kDa (322aa) confirmed by MALDI-TOF

Additionnal Information

SULT1C4, Sulfotransferase 1C4, SuLT1C, SuLT1C2, ATGP2110-10 µg, ATGP2110-20 µg, ATGP2110-50 µg, ATGP2110-100 µg, ATGP2110-250 µg, ATGP2110-500 µg, ATGP2110-1 mg, ATGP2110-10, ATGP2110-20, ATGP2110-50, ATGP2110-100, ATGP2110-250, ATGP2110-500, ATGP2110-1

References & Citations

Sakakibara Y., et al. (1998) J Biol Chem. 273 (51) :33929-35

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 20% glycerol, 1mM DTT

Scientific Category

Metabolism

NCBI Accession Number

NP_006579

Uniprot Accession Number

O75897

Species

Human

AA Sequence

MALHDMEDFT FDGTKRLSVN YVKGILQPTD TCDIWDKIWN FQAKPDDLLI STYPKAGTTW TQEIVELIQN EGDVEKSKRA PTHQRFPFLE MKIPSLGSGL EQAHAMPSPR ILKTHLPFHL LPPSLLEKNC KIIYVARNPK DNMVSYYHFQ RMNKALPAPG TWEEYFETFL AGKVCWGSWH EHVKGWWEAK DKHRILYLFY EDMKKNPKHE IQKLAEFIGK KLDDKVLDKI VHYTSFDVMK QNPMANYSSI PAEIMDHSIS PFMRKGAVGD WKKHFTVAQN ERFDEDYKKK MTDTRLTFHF QF