Recombinant human RABL5/IFT22 protein
Rab-like protein 5 isoform a, also known as RABL5, is a member of the Ras superfamily of small GTP-binding proteins. The Ras-related superfamily of guanine nucleotide binding proteins includes the R-Ras, Rap, Ral/Rec and Rho/Rab subfamilies. Increasing data suggests an important role for Rab proteins in either endocytosis or in biosynthetic protein transport. The process of transporting newly synthesized proteins from the endoplasmic reticulum to various stacks of the Golgi complex and to secretory vesicles involves the movement of carrier vesicles and requires Rab protein function. Recombinant human RABL5 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Intraflagellar transport 22, Intraflagellar transport protein 22 homolog, Rab-like protein 5, RAB member RAS oncogene family-like 5, FAP9, CFAP9
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by Bradford assay)
Purity
> 95% by SDS-PAGE
Molecular Weight
23.2 kDa (208a) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Adhiambo C., et al. (2009) J Cell Sci. 122:834-41
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 10% glycerol, 1mM DTT
Scientific Category
Signal Transduction
NCBI Accession Number
NP_073614.1
Uniprot Accession Number
Q9H7X7
Species
Human
AA Sequence
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