Recombinant human PF4/CXCL4 protein
CXCL4 is a member of the CXC chemokine family. This chemokine is released from the alpha granules of activated platelets in the form of a homotetramer which has high affinity for heparin and is involved in platelet aggregation. This protein is chemotactic for numerous other cell type and also functions as an inhibitor of hematopoiesis, angiogenesis and T-cell function. Recombinant human CXCL4 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Platelet factor 4, C-X-C motif chemokine 4, Iroplact, Oncostatin-A, Chemokine (C-X-C motif) ligand 4, SCYB4
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.25 mg/mL (determined by Bradford assay)
Purity
> 85% by SDS-PAGE
Molecular Weight
10 kDa (91aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Zhang X., et al. (1994) Biochemistry 33:8361-8366.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 50% glycerol, 2mM DTT
Scientific Category
Hormones & Cytokines
NCBI Accession Number
NP_002610.1
Uniprot Accession Number
P02776
Species
Human
AA Sequence
EAEEDGDLQ CLCVKTTSQV RPRHITSLEV IKAGPHCPTA QLIATLKNGR KICLDLQAPL YKKIIKKLLE S
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