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Recombinant human PF4/CXCL4 protein

CXCL4 is a member of the CXC chemokine family. This chemokine is released from the alpha granules of activated platelets in the form of a homotetramer which has high affinity for heparin and is involved in platelet aggregation. This protein is chemotactic for numerous other cell type and also functions as an inhibitor of hematopoiesis, angiogenesis and T-cell function. Recombinant human CXCL4 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Platelet factor 4, C-X-C motif chemokine 4, Iroplact, Oncostatin-A, Chemokine (C-X-C motif) ligand 4, SCYB4

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.25 mg/mL (determined by Bradford assay)

Purity

> 85% by SDS-PAGE

Molecular Weight

10 kDa (91aa) confirmed by MALDI-TOF

Additionnal Information

CXCL4, PF4, Chemokine (C-X-C motif) ligand 4, PF4, MGC138298, SCYB4, ATGP2105-10 µg, ATGP2105-20 µg, ATGP2105-50 µg, ATGP2105-100 µg, ATGP2105-250 µg, ATGP2105-500 µg, ATGP2105-1 mg, ATGP2105-10, ATGP2105-20, ATGP2105-50, ATGP2105-100, ATGP2105-250, ATGP2105-500, ATGP2105-1

References & Citations

Zhang X., et al. (1994) Biochemistry 33:8361-8366.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 50% glycerol, 2mM DTT

Scientific Category

Hormones & Cytokines

NCBI Accession Number

NP_002610.1

Uniprot Accession Number

P02776

Species

Human

AA Sequence

EAEEDGDLQ CLCVKTTSQV RPRHITSLEV IKAGPHCPTA QLIATLKNGR KICLDLQAPL YKKIIKKLLE S

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