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Recombinant human NUDT4/DIPP2 protein

NUDT4 regulates the turnover of diphosphoinositol polyphosphates. The turnover of these high-energy diphosphoinositol polyphosphates represents a molecular switching activity with important regulatory consequences. Molecular switching by diphosphoinositol polyphosphates may contribute to regulating intracellular trafficking. Recombinant human NUDT4 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

Product Specifications

Product Name Alternative

Nudix hydrolase 4, Diadenosine 5',5'''-P1, P6-hexaphosphate hydrolase 2, Nucleoside diphosphate-linked moiety X motif 4, Nudix motif 4, Diphosphoinositol polyphosphate phosphohydrolase 2, DIPP2, DIPP2alpha, DIPP2beta, HDCMB47P

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

22.7 kDa (203aa) confirmed by MALDI-TOF

Additionnal Information

NuDT4, Diphosphoinositol polyphosphate phosphohydrolase 2, DIPP2, DIPP2alpha, DIPP2beta, HDCMB47P, ATGP2100-10 µg, ATGP2100-20 µg, ATGP2100-50 µg, ATGP2100-100 µg, ATGP2100-250 µg, ATGP2100-500 µg, ATGP2100-1 mg, ATGP2100-10, ATGP2100-20, ATGP2100-50, ATGP2100-100, ATGP2100-250, ATGP2100-500, ATGP2100-1

References & Citations

Caffrey JJ. et al. (2000) J Biol Chem. 275:12730-12736; ; Caffrey JJ. et al. (2001) Gene. 269 :53-60.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 0.1M NaCl

Scientific Category

Signal Transduction

NCBI Accession Number

NP_061967.3

Uniprot Accession Number

Q9NZJ9

Species

Human

AA Sequence

MMKFKPN QTRTYDREGF KKRAACLCFR SEQEDEVLLV SSSRYPDQWI VPGGGMEPEE EPGGAAVREV YEEAGVKGKL GRLLGIFENQ DRKHRTYVYV LTVTEILEDW EDSVNIGRKR EWFKVEDAIK VLQCHKPVHA EYLEKLKLGC SPANGNSTVP SLPDNNALFV TAAQTSGLPS SVR

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