Recombinant human FGF-17 protein

FGF17 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes including embryonic development cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was shown to be prominently expressed in the cerebellum and cortex. The mouse homolog of this gene was localized to specific sites in the midline structures of the forebrain, the midbrain-hindbrain junction, developing skeleton and developing arteries, which suggests a role in central nervous system, bone and vascular development. Recombinant human FGF17 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Product Specifications

Product Name Alternative

Fibroblast growth factor 17, FGF-13

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE, Denatured

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

25.2 kDa (219aa)

Additionnal Information

FGF17, Fibroblast growth factor 17, FGF-13, ATGP2092-10 µg, ATGP2092-20 µg, ATGP2092-50 µg, ATGP2092-100 µg, ATGP2092-250 µg, ATGP2092-500 µg, ATGP2092-1 mg, ATGP2092-10, ATGP2092-20, ATGP2092-50, ATGP2092-100, ATGP2092-250, ATGP2092-500, ATGP2092-1

References & Citations

Zhang X., et al. (2006) J. Biol. Chem. 281:15694-15700; ; Turner N., et al. (2010) Nat. Rev. Cancer. 10:116-129

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol

Scientific Category

Hormones & Cytokines

NCBI Accession Number

NP_003858

Uniprot Accession Number

O60258

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MGSHMTQGEN HPSPNFNQYV RDQGAMTDQL SRRQIREYQL YSRTSGKHVQ VTGRRISATA EDGNKFAKLI VETDTFGSRV RIKGAESEKY ICMNKRGKLI GKPSGKSKDC VFTEIVLENN YTAFQNARHE GWFMAFTRQG RPRQASRSRQ NQREAHFIKR LYQGQLPFPN HAEKQKQFEF VGSAPTRRTK RTRRPQPLT