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Recombinant human DGCR6L protein

DGCR6L is a protein that shares homology with the Drosophila gonadal protein, expressed in gonadal tissues and germ cells, and with the human laminin gamma-1 chain that functions in cell attachment and migration. This protein is located in a region of chromosome 22 implicated in the DiGeorge syndrome, one facet of a broader collection of anomalies referred to as the CATCH 22 syndrome. Recombinant human DGCR6L protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Gem-associated protein 6, gem (nuclear organelle) associated protein 6

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by Bradford assay)

Purity

> 85% by SDS-PAGE

Molecular Weight

27.3 kDa (243aa) confirmed by MALDI-TOF

Additionnal Information

DGCR6L, Gem-associated protein 6, gem (nuclear organelle) associated protein 6, ATGP2085-10 µg, ATGP2085-20 µg, ATGP2085-50 µg, ATGP2085-100 µg, ATGP2085-250 µg, ATGP2085-500 µg, ATGP2085-1 mg, ATGP2085-10, ATGP2085-20, ATGP2085-50, ATGP2085-100, ATGP2085-250, ATGP2085-500, ATGP2085-1

References & Citations

Li, X., et al. (2010) Int. J. Biochem. Cell Biol. 42 (1), 70-79; ; Pfuhl, T., et al. (2005) Hum. Genet. 117 (1), 70-80

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 50% glycerol, 1mM DTT, 250 mM Imidazole

Scientific Category

Other

NCBI Accession Number

NP_150282

Uniprot Accession Number

Q9BY27

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MGSMERYAAA LEEVADGARQ QERHYQLLSA LQSLVKELPS SFQQRLSYTT LSDLALALLD GTVFEIVQGL LEIQHLTEKS LYNQRLRLQN EHRVLRQALR QKHQEAQQAC RPHNLPVVQA AQQRELEAVE HRIREEQRAM DQKIILELDR KVADQQSTLE KAGVAGFYVT TNPQELMLQM NLLELIRKLQ QRGCRAGNAA LGLGGPWQSP AAQCDQKGSP VPP

Frequently Asked Questions

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