Recombinant human DGCR6L protein
DGCR6L is a protein that shares homology with the Drosophila gonadal protein, expressed in gonadal tissues and germ cells, and with the human laminin gamma-1 chain that functions in cell attachment and migration. This protein is located in a region of chromosome 22 implicated in the DiGeorge syndrome, one facet of a broader collection of anomalies referred to as the CATCH 22 syndrome. Recombinant human DGCR6L protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Gem-associated protein 6, gem (nuclear organelle) associated protein 6
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by Bradford assay)
Purity
> 85% by SDS-PAGE
Molecular Weight
27.3 kDa (243aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Li, X., et al. (2010) Int. J. Biochem. Cell Biol. 42 (1), 70-79; ; Pfuhl, T., et al. (2005) Hum. Genet. 117 (1), 70-80
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 50% glycerol, 1mM DTT, 250 mM Imidazole
Scientific Category
Other
NCBI Accession Number
NP_150282
Uniprot Accession Number
Q9BY27
Species
Human
AA Sequence
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