Recombinant human SVH/ARMC10 protein
AMRC10 is a protein that contains an armadillorepeat and transmembrane domain. The protein decreases the transcriptional activity of the tumor suppressor protein p53 through direct interaction with the DNA-binding domain of p53, and may play a role in cell growth and survival. upregulation of this gene may play a role in hepatocellular carcinoma. Recombinant human AMRC10 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Armadillo repeat-containing protein 10 isoform b, PNAS-112, PNAS112, PSEC0198, SVH
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 85% by SDS-PAGE
Molecular Weight
33.6 kDa (304aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Zhou, X., et al. (2007) FEBS Lett. 581 (25), 4943-4948; ; Huang, R., et al. (2003) Cancer Res. 63 (13), 3775-3782
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT
Scientific Category
Cancer
NCBI Accession Number
NP_001154481
Uniprot Accession Number
Q8N2F6
Species
Human
AA Sequence
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