Recombinant human RhoQ protein
RHOQ, also known as rho-related GTP-binding protein RhoQ, is a small signaling G protein (more specifically a GTPase), and is a member of the Rac subfamily of the family Rho family of GTPases. It involved in epithelial cell polarization processes. It may play a role in CFTR trafficking to the plasma membrane. It causes the formation of thin, actin-rich surface projections called filopodia. Recombinant human RhoQ protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.
Product Specifications
Product Name Alternative
Rho-related GTP-binding protein RhoQ, ras homolog family member Q, RAS-like, family 7 member A, RASL7A, Ras-like protein TC10, ARHQ
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by Bradford assay)
Purity
> 85% by SDS-PAGE
Molecular Weight
24.7 kDa (225aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Ridley AJ. et al. (2006) Trends Cell Biol. 16:522-529; ; Cheng J. et al. (2005) J Biol Chem. 280:3731-3739.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 1mM DTT
Scientific Category
Signal Transduction
NCBI Accession Number
NP_036381
Uniprot Accession Number
P17081
Species
Human
AA Sequence
Frequently Asked Questions
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