Recombinant human IL-17B protein

IL17B is a T cell-derived cytokine that shares sequence similarity with IL17. This cytokine was reported to stimulate the release of TNF alpha (TNF) and IL1 beta (IL1B) from a monocytic cell line. Immunohistochemical analysis of several nerve tissues indicated that this cytokine is primarily localized to neuronal cell bodies. Recombinant human IL17B protein, fused to His-tag at N-terminus, was expressed in E. coli.

Product Specifications

Product Name Alternative

Interleukin 17B, IL-17B, Cytokine Zcyto7, Interleukin-20, IL-20, Neuronal interleukin-17-related factor, NIRF, ZCYTO7

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE, Denatured

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

20 kDa (185aa)

Additionnal Information

ZCYTO7, NIRF, Neuronal interleukin-17-related factor, Neuronal interleukin 17 related factor, Interleukin-20, Interleukin20, Interleukin 20, Interleukin-17B precursor, Interleukin-17B isoform 1, Interleukin 17B precursor, Interleukin 17B isoform 1, Interleukin17B, Interleukin-17B, Interleukin 17B, IL-20, IL 20, IL20, IL-17B, IL 17B, IL17B, Cytokine Zcyto7, ATGP2077-10 µg, ATGP2077-20 µg, ATGP2077-50 µg, ATGP2077-100 µg, ATGP2077-250 µg, ATGP2077-500 µg, ATGP2077-1 mg, ATGP2077-010, ATGP2077-020, ATGP2077-050, ATGP2077-100, ATGP2077-250, ATGP2077-500, ATGP2077-01M

References & Citations

T.A. Moseley1, D.R. Haudenschild1, et al. (2003) . Cytokine & Growth Factor Reviews 14 (2003) 155-174

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol

Scientific Category

Hormones & Cytokines

NCBI Accession Number

NP_055258

Uniprot Accession Number

Q9UHF5

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MGSHMQPRSP KSKRKGQGRP GPLAPGPHQV PLDLVSRMKP YARMEEYERN IEEMVAQLRN SSELAQRKCE VNLQLWMSNK RSLSPWGYSI NHDPSRIPVD LPEARCLCLG CVNPFTMQED RSMVSVPVFS QVPVRRRLCP PPPRTGPCRQ RAVMETIAVG CTCIF